| # | Title | Dec 25 - 27 | % Chg. | Theaters | Weeks | AVG | Cumulative | ||
| 1 | Avatar | $ 75,617,133 | -1.8 | 3,456 | 2 | $ 21,880 | $ 212,711,184 | ||
| 2 | Sherlock Holmes | 62,390,000 | 3,626 | 1 | 17,206 | 62,390,000 | |||
| 3 | Alvin and the Chipmunks: The Squeakquel | 48,875,415 | 3,700 | 1 | 13,210 | 75,589,048 | |||
| 4 | It's Complicated | 22,100,820 | 2,887 | 1 | 7,655 | 22,100,820 | |||
| 5 | The Blind Side | 11,470,000 | 14.5 | 2,766 | 6 | 4,147 | 184,127,000 | ||
| 6 | Up in the Air | 11,275,000 | 251.2 | 1,895 | 4 | 5,950 | 24,038,000 | ||
| 7 | The Princess and the Frog | 9,004,610 | -26.1 | 3,475 | 5 | 2,591 | 63,679,289 | ||
| 8 | Nine | 5,452,513 | 1,412 | 2 | 3,862 | 5,830,605 | |||
| 9 | Did You Hear About the Morgans? | 5,000,143 | -24.4 | 2,718 | 2 | 1,840 | 15,600,328 | ||
| 10 | Invictus | 4,045,000 | -3.8 | 2,160 | 3 | 1,873 | 23,020,000 |
Source: Box Ofice Guru
