| # | Title | Jan 8 - 10 | % Chg. | Theaters | Weeks | AVG | Cumulative | ||
| 1 | Avatar | $ 50,306,217 | -26.6 | 3,422 | 4 | $ 14,701 | $ 430,846,514 | ||
| 2 | Sherlock Holmes | 16,585,327 | -54.7 | 3,626 | 3 | 4,574 | 165,153,093 | ||
| 3 | Alvin and the Chipmunks: The Squeakquel | 16,566,489 | -52.9 | 3,641 | 3 | 4,550 | 178,451,165 | ||
| 4 | Daybreakers | 15,146,692 | 2,523 | 1 | 6,003 | 15,146,692 | |||
| 5 | It's Complicated | 11,007,875 | -41.5 | 2,955 | 3 | 3,725 | 76,370,540 | ||
| 6 | Leap Year | 9,202,815 | 2,511 | 1 | 3,665 | 9,202,815 | |||
| 7 | The Blind Side | 7,531,467 | -36.8 | 2,880 | 8 | 2,615 | 218,978,376 | ||
| 8 | Up in the Air | 7,159,294 | -33.2 | 2,218 | 6 | 3,228 | 54,800,688 | ||
| 9 | Youth in Revolt | 6,888,334 | 1,873 | 1 | 3,678 | 6,888,334 | |||
| 10 | The Princess and the Frog | 4,651,156 | -52.7 | 2,620 | 7 | 1,775 | 92,546,727 |
Source: Box OFfice Guru
