| # | Title | May 1 - 3 | % Chg. | Theaters | Weeks | AVG | Cumulative | ||
| 1 | X-Men Origins: Wolverine | $ 85,058,003 | 4,099 | 1 | $ 20,751 | $ 85,058,003 | |||
| 2 | Ghosts of Girlfriends Past | 15,411,434 | 3,175 | 1 | 4,854 | 15,411,434 | |||
| 3 | Obsessed | 12,052,151 | -57.9 | 2,514 | 2 | 4,794 | 46,854,485 | ||
| 4 | 17 Again | 6,361,358 | -44.8 | 3,255 | 3 | 1,954 | 48,503,817 | ||
| 5 | Monsters vs. Aliens | 5,803,429 | -31.9 | 2,626 | 6 | 2,210 | 182,407,971 | ||
| 6 | The Soloist | 5,654,558 | -41.8 | 2,033 | 2 | 2,781 | 18,162,696 | ||
| 7 | Earth | 4,340,235 | -50.8 | 1,804 | 2 | 2,406 | 22,004,284 | ||
| 8 | Hannah Montana The Movie | 4,164,185 | -35.3 | 2,819 | 4 | 1,477 | 70,946,323 | ||
| 9 | Fighting | 4,011,465 | -63.6 | 2,312 | 2 | 1,735 | 17,344,805 | ||
| 10 | State of Play | 3,715,980 | -45.7 | 2,445 | 3 | 1,520 | 30,944,180 | ||
Source: Box Office Guru
